Tocris™ L-755,507

Very potent and selective beta3 partial agonist

Manufacturer: Tocris™ 2197/50

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Catalog No. 21-975-0

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For Research Use Only


    Specifications

    Product Type L-755,507
    Inhibitors L-755,507
    Purity >98
    Molecular Weight 584.73
    Quantity 50mg

    Potent β3-adrenergic receptor partial agonist > 1000-fold selective over β1- and β2-adrenoceptors (EC50 values are 0.43, 580 and > 10000nM for activation of cloned human β3-, β1- and β2-adrenoceptors respectively). Stimulates lipolysis in rhesus adipocytes in vitro (EC50 = 3.9nM). Enhances CRISPR-mediated homology-directed repair (HDR) efficiency in human induced pluripotent stem cells (iPSCs).

    • Chemical Name: 4-[[(Hexylamino)carbonyl]amino]-N-[4-[2-[[(2S)-2-hydroxy-3-(4-hydroxyphenoxy)propyl]amino]ethyl]phenyl]-benzenesulfonamide
    • Formula: C30H40N4O6S
    • CAS Number: 159182-43-1
    • Solubility: Soluble to 100mM in DMSO and to 100mM in ethanol
    • Purity: >98

  • Description & Specifications

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