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L-Selectin/CD62L Mouse anti-Bovine, Janelia Fluor 549, Clone: FMC46, Novus Biologicals™

Mouse Monoclonal Antibody

Manufacturer:  Novus Biologicals NB10065388JF549

Catalog No. NB065388549



L-Selectin/CD62L Monoclonal antibody specifically detects L-Selectin/CD62L in Bovine samples. It is validated for Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Frozen.


Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Frozen
PHA stimulated lymphoblasts.
Protein G purified
Adaptive Immunity, B Cell Development and Differentiation Markers, Immunology, Lipid and Metabolism, Myeloid derived Suppressor Cell, Signal Transduction
Bovine, Canine, Human, Primate
Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Frozen)
Janelia Fluor 549
50mM Sodium Borate with 0.05% Sodium Azide
CD62L, CD62L antigen, gp90-MEL, hLHRc, LAM-1, LAM1LECAM1, Leu-8, LEU8, Leukocyte adhesion molecule 1, Leukocyte surface antigen Leu-8, Leukocyte-endothelial cell adhesion molecule 1, LNHRTQ1, LSEL, L-selectin, Lyam-1, LYAM1CD62 antigen-like family member L, Lymph node homing receptor, lymphocyte adhesion molecule 1, pln homing receptor, PLNHR, selectin L
Store at 4°C in the dark.
NB100-65388 recognizes human CD62L, also known a L-selectin, a 74-95kDa member of the selectin family of adhesion receptors, which acts as a ligand for both CD62-P (P-selectin) and CD62E (E-selectin). Human CD62L is constitutively expressed on most leucocytes including monocytes, granulocytes, lymphocytes, NK cells, bone marrow myeloid progenitor cells and on a subset of thymocytes. CD62L plays an important role in leucocyte tethering and rolling on the endothelial cell surface and for the homing of naive lymphocytes to lymph nodes and Peyers patches via HEV. Neutrophils require a constant supply of this molecule on the cell surface for migration into peripheral tissues and adhesion to activated endothelium at sites of inflammation, where CD62L is rapidly shed as soluble L-selectin, but surface expression still remains. The expression of CD62L is down regulated on lymphocytes and neutrophils by PMA stimulation.
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