α-1-Antitrypsin Ab-1 Rabbit Polyclonal Antibody, Epredia™
Obtain accurate, reproducible results with Epredia™ α-1-Antitrypsin Ab-1, Rabbit Polyclonal Antibody.
Manufacturer: Epredia RB367R7
Alpha-1-AT is synthesized in the liver and it acts as an inhibitor of proteases such as trypsin, elastase, chymotrypsin, collagenase, leucocytic proteases, plasmin, and thrombin, which may be released during inflammatory reactions in the lung. In the absence of alpha-1-AT, these enzymes are not inhibited and they may digest pulmonary parenchyma. Alpha-1-AT deficiency is associated with chronic obstructive lung disease (emphysema) and less frequently with hepatic cirrhosis in infants and respiratory distress of the newborn. Increase in alpha-1-AT occurs as an acute phase response to tissue necrosis and inflammation. Serum level of alpha-1-AT is elevated in rheumatoid arthritis, bacterial infections, vasculitis, and carcinomatosis.
Host Species: Rabbit
Species Reactivity: Human, Baboon, Monkey, Horse and Mink. Does not react with cow, kangaroo, pig, goat, sheep, cat, dog, guinea pig, mouse and chicken. Others not known.
Immunogen: Purified human serum α-1-AT
Positive Control: Tonsil
Cellular Localization: Cytoplasmic
- Immunohistochemistry (Formalin/paraffin)
USA: RUO; Int'l: RUO
|Purified human serum alpha-1-AT|
|Ready to Use|
|Baboon, Equine, Human, Mink|
We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.
Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.Ok