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Epredia™ Lab Vision™ 14.3.3σ Ab-1 Mouse Monoclonal Antibody, 200μg/mL, BSA and azide

Take advantage of a quality product that delivers accurate results with the Epredia™ 14.3.3σ Ab-1, Mouse Monoclonal Antibody.

Supplier:  Epredia™ MS1185R7

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Catalog No. MS1185R7


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Description

Description

14.3.3 proteins are a family of small, widely expressed, highly conserved cytosolic proteins. 14.3.3 proteins bind to and influence the activities of a diverse group of molecules involved in signal transduction, cell cycle regulation and apoptosis, including Raf, PKC, Bad, Cbl, and c-Bcr. Interactions between 14.3.3 and target proteins are strongly influenced by the phosphorylation state of 14.3.3 and the target protein. 14.3.3 σ shares cyclin-Cdk2 binding motifs with different cell cycle regulators, including p107, p130, p21Cip1, p27Kip1, and p57Kip2 and is associated with cyclin-Cdk complexes in vitro and in vivo.

Host Species: Mouse

Clone: 1433S01

Isotype: IgG1/κ

Species Reactivity: Human. Others not tested.

Epitope: Not determined

Immunogen: Recombinant human 14.3.3σ protein

Molecular Weight: 26-30kDa

Positive Control: HT29 cells, Skin

Cellular Localization: Cytoplasmic

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunofluorescence
  • Immunoprecipitation

Note:

USA: RUO; Int'l: RUO

Specifications

Specifications

14.3.3sigma Ab-1
Monoclonal
Unconjugated
Recombinant human 1433 sigma protein
RUO
Primary
Prediluted
Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
1433S01
Mouse
7 mL
Signal Transduction
Human
IgG2a κ
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