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Epredia™ Lab Vision™ ALK (Anaplastic Lymphoma Kinase)/p80 Rabbit Monoclonal Antibody

Obtain accurate, reproducible results in immunohistochemistry experiments with Epredia™ ALK (Anaplastic Lymphoma Kinase)/p80, Rabbit Monoclonal Antibody.

Manufacturer:  Epredia™ RM9108R7

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Catalog No. RM9108R7

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

Recognizes a human p80 protein, identified as a hybrid of the anaplastic lymphoma kinase (ALK) gene and the nucleophosmin (NPM) gene resulting from the t(2;5)(p23;q35) translocation found in 30-50% of CD30+ large cell lymphomas (1). This rabbit monoclonal antibody can be used to detect p80 in these lymphomas and may also be used to detect a recently described subtype of large B cell lymphoma, which expresses the full-length ALK protein (2).

Host Species: Rabbit

Clone: SP8

Isotype: IgG

Species Reactivity: Human. Others not tested.

Epitope: Not determined

Immunogen: Recombinant protein corresponding to a region which spans the tyrosine kinase catalytic domain and part of the C-terminus of the NPM-ALK transcript

Positive Control: Anaplastic lymphoma

Cellular Localization: Cytoplasmic + nuclear Clone SP8 is excellent for staining of formalin/paraffin with no special pretreatment

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
Specifications

Specifications

ALK (Anaplastic Lymphoma Kinase)/p80
Monoclonal
Unconjugated
Recombinant protein corresponding to a region, which spans the tyrosine kinase catalytic domain and part of the C-terminus of the NPM-ALK transcript
IVD
Primary
Prediluted
Immunohistochemistry (Paraffin)
SP8
Rabbit
7 mL
Cancer and Tumor Biology
Human
IgG
SDS
Documents
Product Certifications
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