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Epredia™ Lab Vision™ Caspase 3 (CPP32) Ab-4 Rabbit Polyclonal Antibody, biotin labeled with BSA and azide
Ensure accurate, reproducible results in immunohistochemistry, western blotting and immunoprecipitation procedures.
Supplier: Epredia™ RB1197P
Description
Caspase 3 is ubiquitously expressed and like other caspases is synthesized as an inactive (32 kDa) proenzyme. Upon activation, Caspase 3 is cleaved at Asp28-Ser29 and Asp175-Ser176 thereby generating two subunits of 17 kDa and 12 kDa, respectively. Recent studies have implicated that Caspase 3 is associated with the induction of apoptosis. Activation of Caspase 3 occurs in response to a variety of apoptotic inducers including Fas-mediated apoptosis.Host Species: Rabbit
Isotype: IgG
Species Reactivity: Human, Mouse, Rat, Monkey, Rabbit, Hamster, Cow, Sheep, Pig and Dog. Others not tested.
Epitope: Not determined
Immunogen: Recombinant full-length human caspase 3 protein
Molecular Weight: 32 kDa
Positive Control: Jurkat cells, Tonsil
Cellular Localization: Predominantly cytoplasmic with some nuclear staining
Recommended for:
- Immunohistochemistry (Formalin/paraffin)
- Western Blotting
- Immunoprecipitation (Denatured verified)
Note:
USA: RUO; Int'l: RUO
Specifications
Caspase 3 (CPP32) Ab-4 | |
Polyclonal | |
Unconjugated | |
Recombinant full length human caspase 3 protein | |
RUO | |
Primary | |
Concentrated |
Immunoprecipitation, Western Blot | |
1mg/mL | |
Rabbit | |
1 mL | |
Apoptosis | |
Bovine, Canine, Hamster, Human, Mouse, Non-human Primate, Porcine, Rabbit, Rat | |
IgG |
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