Epredia™ Lab Vision™ Caspase 6 (Mch 2) Ab-3 Mouse Monoclonal Antibody, 200μg/mL, BSA and Azide

Ensure accurate, reproducible results in western blotting and immunoprecipitation procedures with Epredia™ Caspase 6 (Mch 2) Ab-3, Mouse Monoclonal Antibody.

Supplier:  Epredia™ MS1126P

Catalog No. MS1126P

Description

Caspases play a major role in the transduction of the apoptotic signal and execution of apoptosis in mammalian cells. Caspase 3 (CPP32) and Caspase 6 (Mch2) are the major active caspases in apoptotic cells, and are activated in response to distinct apoptosis-inducing stimuli in all cell lines analyzed. Both CPP32 and Mch2 are present in apoptotic cells as multiple active species. Caspase-6 cleaves nuclear mitotic apparatus protein (NuMA) and mediates the shrinkage and fragmentation of nuclei.

Host Species: Mouse

Clone: 6CSP03; same as 14.1.190

Isotype: IgG1/κ

Species Reactivity: Human. Others not tested.

Epitope: Caspase 6 prodomain

Immunogen: Recombinant human caspase 6 prodomain

Molecular Weight: 34 kDa

Positive Control: Jurkat cells

Cellular Localization: Cytoplasmic

Recommended for:

• Western Blotting
• Immunoprecipitation

Note:

USA: RUO; Int'l: RUO

Specifications

• Antigen: Caspase 6 (Mch 2) Ab-3
• Classification: Monoclonal
• Concentration: 200μg/mL
• Host Species: Mouse
• Quantity: 1 mL
• Research Discipline: Apoptosis
• Target Species: Human
• Isotype: IgG2a κ

• Applications: Immunoprecipitation, Western Blot
• Clone: 6CSP03; same as 14.1.190
• Conjugate: Unconjugated
• Immunogen: Recombinant human caspase 6 prodomain
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Form: Concentrated