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CD45/T200/LCA Ab-2 Mouse Monoclonal Antibody, Epredia™

Ensure accurate, reproducible results in immunohistochemistry, immunofluorescence, and flow cytometry experiments.

Supplier:  Epredia MS355P

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Catalog No. MS355P


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Description

Description

CD45 leucocyte common antigen (LCA) belongs to the family of at least four isoforms of membrane glycoproteins (220, 205, 190, 180 kDa) expressed on hematopoietic cell lines but absent on non-hematopoietic cell lines, normal and malignant non-hematopoietic tissues. The intracellular portion of these molecules have protein phosphatase activity and are involved in regulation of transmembrane signals. Antibody to CD45 is useful in differential identification of lymphoid tumors from non-hematopoietic undifferentiated neoplasms.

Host Species: Mouse

Clone: PD7/26/16 + 2B11

Isotype: IgG1/κ

Species Reactivity: Human. Does not react with rat and dog. Others not known

Epitope: Not determined

Immunogen: PD7/26/16: human peripheral blood lymphocytes maintained in T-cell growth factor. 2B11: isolated neoplastic cells from T-cell lymphoma

Molecular Weight: 220, 205, 190, 180 kDa

Positive Control: Tonsil

Cellular Localization: Membrane

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Immunofluorescence
  • Flow Cytometry
Specifications

Specifications

CD45/T200/LCA Ab-2
Monoclonal
200μg/mL
Mouse
1 mL
Oncogenesis
Human
IgG2a κ
Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin)
PD7/26/16 + 2B11
Unconjugated
PD7/26/16: human peripheral blood lymphocytes maintained in T cell growth factor. 2B11: isolated neoplastic cells from T cell lymphoma.
IVD
Primary
Concentrated
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