Epredia™ Lab Vision™ CD8, Rabbit Polyclonal Antibody

Ensure accurate and reproducible results in immunohistochemistry experiments with Epredia™ CD8, Rabbit Polyclonal Antibody.

Supplier:  Epredia™ RB9009R1

Catalog No. RB9009R1

Description

CD8 molecule consists of two chains, termed alpha and Beta chain, which are expressed as a disulphide-linked alpha/Beta heterdimer or as an alpha/alpha homodimer on T cell subset, thymocytes and NK cells. The majority of CD8+ T cells express CD8 as alpha/Beta heterdimer. CD8 functions as a coreceptor in concert with TCR for binding the MHC class I/peptide complex. The HIV-2 envelope glycoprotein binds CD8 alpha chain (but not Beta chain).

Host Species: Rabbit

Isotype: IgG

Species Reactivity: Human. Others not tested.

Epitope: C-terminus

Immunogen: Synthetic peptide sequence comprising the 13 C-terminal amino acids of the cytoplasmic domain of α-chain of the CD8 molecule

Positive Control: Tonsil

Cellular Localization: Membrane

Recommended for:

• Immunohistochemistry (Formalin/paraffin)

Specifications

• Antigen: CD8
• Classification: Polyclonal
• Host Species: Rabbit
• Quantity: 1 mL
• Research Discipline: T-Cell
• Target Species: Human
• Isotype: IgG

• Applications: Immunohistochemistry (Paraffin)
• Conjugate: Unconjugated
• Immunogen: Synthetic peptide sequence comprising the 13 C-terminal amino acids of the cytoplasmic domain of alpha chain of the CD8 molecule
• Regulatory Status: IVD
• Primary or Secondary: Primary
• Form: Prediluted