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Epredia™ Lab Vision™ E-Cadherin Rabbit Monoclonal Antibody

Ensure accurate and reliable results in immunohistochemistry applications with Epredia™ Cadherin E, Rabbit Monoclonal Antibody.

Supplier:  Epredia™ RM2100S0

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Catalog No. RM2100S0


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Description

Description

E-cadherin (uvomorulin, cell-CAM120/80) is a calcium-dependent cell adhesion molecule expressed predominantly in epithelial tissues. It plays an important role in the growth and development of cells via the mechanisms of control of tissue architecture and the maintenance of tissue integrity. Numerous studies have demonstrated that reduction and/or loss of E-cadherin expression in carcinomas correlates positively with the potential of these tumors for invasion and metastasis. E-cadherin is used in distinguishing LCIS from DCIS and that of ILC from IDC in indeterminate cases.

Host Species: Rabbit

Clone: EP700Y

Species Reactivity: Human. Others not known.

Immunogen: A synthetic peptide derived from the fifth cadherin domain of human cadherin

Molecular Weight: 135/80kDa

Positive Control: Breast Carcinoma

Cellular Localization: Cell Membrane

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
Specifications

Specifications

E-Cadherin
Monoclonal
Unconjugated
A synthetic peptide derived from the fifth cadherin domain of human cadherin
IVD
Primary
Concentrated
Immunohistochemistry (Paraffin)
EP700Y
Rabbit
100 μL
Cancer and Tumor Biology
Human
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