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Factor VIII Related Antigen/von Willebrand Factor Ab-2 Mouse Monoclonal Antibody, Epredia™

Ensure accurate, reproducible results in immunohistochemistry experiments.

$388.00 - $515.00

Specifications

Antigen Factor VIII Related Antigen/von Willebrand Factor Ab-2
Clone F8/86
Applications Immunohistochemistry (Paraffin)
Classification Monoclonal
Conjugate Unconjugated
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Products 8
Catalog Number Mfr. No. Formulation Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Formulation Quantity Price Quantity & Availability  
MS722P
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Epredia
MS722P
Purified Ab with BSA and Azide 1mL
Each for $473.00
Add to cart
 
MS722P1
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Epredia
MS722P1
Purified Ab with BSA and Azide 500μL
Each for $388.00
Add to cart
 
MS722P1ABX
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Epredia
MS722P1ABX
Ab without BSA/Azide (Frozen) 100μL
Each for $435.00
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MS722PABX
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Epredia
MS722PABX
Ab without BSA/Azide (Frozen) 200μL
Each for $515.00
Add to cart
 
MS722R1
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Epredia
MS722R1
Ready-to-use for IHC (UVLP) 1mL This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000. N/A
MS722P0
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Epredia
MS722P0
Purified Ab with BSA and Azide 100μL This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000. N/A
MS722R7
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Epredia
MS722R7
Ready-to-use for IHC (UVLP) 7mL This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000. N/A
MS722RQ
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Epredia
MS722RQ
Ready-to-use for IHC (Quanto) 12mL This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000. N/A
Description

Description

Factor VIII related antigen or von Willebrand factor is a multimeric glycoprotein, which binds to platelet glycoprotein Ib, glycoprotein IIb/IIIa, collagen and heparin. It is synthesized by endothelial cells and stored in the Weibel-Palade granules. It mediates platelet adhesion to injured vessel walls and serves as a carrier and stabilizer for coagulation factor VIII. von Willebrand factor is one of the most useful markers to identify endothelial (or megakaryocytic) lineage of neoplasms. As not all endothelial cells synthesize/store this molecule, about 30% of tumors of vascular origin fail to stain for factor VIII related antigen, regardless of whether they are benign or malignant. Staining for factor VIII related antigen has also been used to measure angiogenesis, an indicator of tumor recurrence.

Host Species: Mouse

Clone: F8/86

Isotype: IgG1/κ

Species Reactivity: Human. Others not known.

Epitope: Not determined

Immunogen: Partially purified von Willebrand factor from human placenta

Molecular Weight: 270 kDa

Positive Control: Blood vessels in tonsil or intestine

Cellular Localization: Cytoplasmic

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)

Specifications

Specifications

Factor VIII Related Antigen/von Willebrand Factor Ab-2
Immunohistochemistry (Paraffin)
Unconjugated
IVD
Primary
F8/86
Monoclonal
Mouse
Hematopoietic
Partially purified von Willebrand factor from human placenta
SDS
Product Certifications
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