DescriptionHuman Chorionic Gonadotropin (HCG) is a glycoprotein that is secreted in large quantities by normal trophoblasts. It is present only in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy. HCG is composed of two non-identical, non-covalently linked polypeptide chains designated as the alpha- and Beta-subunits. The alpha-subunit of HCG is nearly identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH), and luteinizing hormone (LH). A germ cell tumor which is positive for cytokeratin, placental alkaline phosphatase (PLAP), and HCG but negative for EMA and AFP is probably a choriocarcinoma.
Host Species: Rabbit
Species Reactivity: Human. Others not known.
Immunogen: Purified β-subunit of hCG
Molecular Weight: 22 kDa
Positive Control: Placenta or chorioca
Cellular Localization: Cytoplasmic
- Immunohistochemistry (Formalin-fixed)
USA: RUO; Int'l: RUO
|Chorionic Gonadotropin, Human/hCG Ab-2|
|Steroids Hormones and Growth Factors|
|Purified Beta-subunit of HCG|
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