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Human Sodium Iodide Symporter (hNIS) Ab-1 Mouse Monoclonal Antibody, Epredia™
Provide accurate, reproducible results with the Epredia™ Human Sodium Iodide Symporter (hNIS) Ab-1, Mouse Monoclonal Antibody.
Supplier: Epredia MS1653R1
Description
Human Sodium Iodide Symporter (hNIS) is responsible for iodide concentrating ability within thyroid follicular cells. It is a membrane bound glycoprotein with 13 membrane spanning domains and 14 extramembranous domains. It may represent an autoantigen in thyroid. Antibody to NIS showed strong immunostaining in Graves tissues, intermediate staining in papillary and follicular thyroid cancer, and no staining in Hurtle cell cancer or in nonthyroidal tissue.Host Species: Mouse
Clone: FP5A
Isotype: IgG1/κ
Species Reactivity: Human. Does not react with mouse and rat. Others not tested.
Epitope: aa 625-643
Immunogen: A synthetic peptide corresponding to aa 625-643 of hNIS protein
Molecular Weight: 97kDa
Positive Control: Thyroid
Cellular Localization: Membrane and cytoplasm
Recommended for:
- Immunohistochemistry (Formalin/paraffin)
- Western Blotting
- Immunoprecipitation (Not verified)
Note:
USA: RUO; Int'l: RUO
Specifications
| Human Sodium Iodide Symporter (hNIS) Ab-1 | |
| Monoclonal | |
| Unconjugated | |
| Mouse | |
| 1 mL | |
| Primary | |
| Prediluted |
| Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot | |
| FP5A | |
| Ready-to-use for IHC (UVLP) | |
| A synthetic peptide corresponding to aa625-643 of hNIS protein | |
| RUO | |
| Human | |
| IgG2a κ |
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