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Human Sodium Iodide Symporter (hNIS) Ab-1 Mouse Monoclonal Antibody, Epredia™

Provide accurate, reproducible results with the Epredia™ Human Sodium Iodide Symporter (hNIS) Ab-1, Mouse Monoclonal Antibody.

Manufacturer:  Epredia MS1653R7

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Catalog No. MS1653R7


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Description

Description

Human Sodium Iodide Symporter (hNIS) is responsible for iodide concentrating ability within thyroid follicular cells. It is a membrane bound glycoprotein with 13 membrane spanning domains and 14 extramembranous domains. It may represent an autoantigen in thyroid. Antibody to NIS showed strong immunostaining in Graves tissues, intermediate staining in papillary and follicular thyroid cancer, and no staining in Hurtle cell cancer or in nonthyroidal tissue.

Host Species: Mouse

Clone: FP5A

Isotype: IgG1/κ

Species Reactivity: Human. Does not react with mouse and rat. Others not tested.

Epitope: aa 625-643

Immunogen: A synthetic peptide corresponding to aa 625-643 of hNIS protein

Molecular Weight: 97kDa

Positive Control: Thyroid

Cellular Localization: Membrane and cytoplasm

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunoprecipitation (Not verified)

Note:

USA: RUO; Int'l: RUO

Specifications

Specifications

Human Sodium Iodide Symporter (hNIS) Ab-1
Monoclonal
Unconjugated
Mouse
7 mL
Primary
Prediluted
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
FP5A
Ready-to-use for IHC (UVLP)
A synthetic peptide corresponding to aa625-643 of hNIS protein
RUO
Human
IgG2a κ
SDS
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Product Certifications
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