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Mouse anti-Human CD59/MACIF/MIRL/Protectin Monoclonal Antibody, Clone: BRA-10G, Epredia™ LabVision
Mouse Monoclonal Antibody
Supplier: Epredia MS507PABX
Description
CD59 (also known as membrane attack complex inhibition factor (MACIF), membrane inhibitor of reactive lysis (MIRL), homologous restriction factor (HRF20), and Protectin) is a glycosyl phosphatidyl-inositol (GPI)-anchored cell surface protein. CD59 is widely distributed on cells in all tissues. It inhibits formation of MAC, thus protecting cells from complement mediated lysis. The expression of CD59 on erythrocytes is important for their survival. Genetic defects in GPI-anchor attachment that cause a reduction or loss of CD59 and CD55 on erythrocytes produce the symptoms of the disease paroxysmal hemoglobulinuria (PNH).
Host Species: Mouse
Clone: BRA-10G
Isotype: IgG1/κ
Cross Reactivity: Human, Others not-known
Epitope: Not determined
Immunogen: Human K562 tumor cells
Molecular Weight: 20kDa
Positive Control: Daudi, CEM, K562, Jurkat, Raji, and human lymphocytes. Lymph node or tonsil.
Cellular Localization: Cell membrane
Flow Cytometry, Immunohistochemistry, Immunoprecipitation
Specifications
| CD59/MACIF/MIRL/Protectin Ab-2 | |
| 1mg/mL | |
| Human K562 tumor cells | |
| Primary | |
| Purified |
| Monoclonal | |
| Mouse | |
| 200 μL | |
| Human | |
| IgG1 κ |
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