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p130Cas Ab-1 Mouse Monoclonal Antibody, Epredia™
Take advantage of a quality product that delivers accurate results with the Epredia™ p130Cas Ab-1, Mouse Monoclonal Antibody.
Supplier: Epredia MS855R7
Description
The p130Cas (Cas for Crk-associated substrate) is a common cellular target of phosphorylation signal via v-Crk and v-Src oncoproteins. p130Cas has a unique structure that contains a Src homology (SH)-3 domain followed by multiple YXXP motifs and a proline-rich region p130Cas is implicated in a variety of biological processes including cell adhesion, cell migration, growth factor stimulation, cytokine receptor engagement and bacterial infection. Physiological functions of p130Cas include cardiovascular development, actin filament assembly and Src-induced cell transformation.Host Species: Mouse
Clone: CAS-14; same as 35B-1A4
Isotype: IgG1/κ
Species Reactivity: Human and Rat. Others not known.
Epitope: Not determined
Immunogen: Recombinant human p130Cas protein
Molecular Weight: 130kDa
Positive Control: MCF-7 Cells, HUVEC cells, Tonsil or breast CA
Cellular Localization: Cytoplasmic
Recommended for:
- Immunohistochemistry (Formalin/paraffin)
- Western Blotting
- Immunoprecipitation (Denatured verified)
Note:
USA: RUO; Int'l: RUO
Specifications
p130superscriptCassuperscript Ab-1 | |
Monoclonal | |
— | |
Mouse | |
MCF-7 cells, HUVEC cells, tonsil or breast CA | |
RUO | |
Primary | |
Prediluted |
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot | |
CAS-14; same as 35B-1A4 | |
Unconjugated | |
Recombinant human p130superscriptCassuperscript protein | |
7 mL | |
Cell Cycle | |
Human, Rat | |
IgG2a κ |
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