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p130Cas Ab-1 Mouse Monoclonal Antibody, Epredia™

Take advantage of a quality product that delivers accurate results with the Epredia™ p130Cas Ab-1, Mouse Monoclonal Antibody.

Supplier:  Epredia MS855R7

 View more versions of this product

Catalog No. MS855R7

Item Discontinued This item has been discontinued by the supplier. Please to view product availability in your area.


Description

Description

The p130Cas (Cas for Crk-associated substrate) is a common cellular target of phosphorylation signal via v-Crk and v-Src oncoproteins. p130Cas has a unique structure that contains a Src homology (SH)-3 domain followed by multiple YXXP motifs and a proline-rich region p130Cas is implicated in a variety of biological processes including cell adhesion, cell migration, growth factor stimulation, cytokine receptor engagement and bacterial infection. Physiological functions of p130Cas include cardiovascular development, actin filament assembly and Src-induced cell transformation.

Host Species: Mouse

Clone: CAS-14; same as 35B-1A4

Isotype: IgG1/κ

Species Reactivity: Human and Rat. Others not known.

Epitope: Not determined

Immunogen: Recombinant human p130Cas protein

Molecular Weight: 130kDa

Positive Control: MCF-7 Cells, HUVEC cells, Tonsil or breast CA

Cellular Localization: Cytoplasmic

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunoprecipitation (Denatured verified)

Note:

USA: RUO; Int'l: RUO

Specifications

Specifications

p130superscriptCassuperscript Ab-1
Monoclonal
Mouse
MCF-7 cells, HUVEC cells, tonsil or breast CA
RUO
Primary
Prediluted
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
CAS-14; same as 35B-1A4
Unconjugated
Recombinant human p130superscriptCassuperscript protein
7 mL
Cell Cycle
Human, Rat
IgG2a κ
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