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p21 WAF1 Ab-11 Mouse Monoclonal Antibody, Epredia™

Ensure accurate, reproducible results with the Epredia™ p21WAF1 Ab-11, Mouse Monoclonal Antibody.

Manufacturer:  Epredia MS891P

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Catalog No. MS891P

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

p21WAF1/Cip1/Sdi1/Pic1 is a tumor suppressor protein. Expression of p21WAF1 is induced by wild type, but not mutant, p53 suppressor protein. The p21WAF1 protein binds to cyclin/CDK complexes and inhibits their kinase activity thereby stopping cell cycle progression. It also binds to PCNA (proliferating cell nuclear antigen) and blocks DNA replication but not the DNA repair process.

Host Species: Mouse

Clone: CP74

Isotype: IgG2b

Species Reactivity: Human and Rat. Others not known.

Epitope: aa 1-80

Immunogen: Full-length human recombinant p21 protein

Molecular Weight: 21kDa

Positive Control: Raji, PC12 cells

Cellular Localization: Nuclear

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunoprecipitation (Native verified)
  • Flow Cytometry

Note:

USA: RUO; Int'l: RUO

Specifications

Specifications

p21superscriptWAF1superscript Ab-11
Monoclonal
200μg/mL
Mouse
1 mL
Cell Cycle
Human, Rat
IgG2b
Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
CP74
Unconjugated
Full length human recombinant p21 protein
RUO
Primary
Concentrated
SDS
Documents
Product Certifications
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