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p21WAF1Ab-3 Mouse Monoclonal Antibody, Epredia™
Achieve accurate, reproducible results with the Epredia™ p21WAF1 Ab-3, Mouse Monoclonal Antibody.
Manufacturer: Epredia MS230PABX
Description
p21WAF1/Cip1/Sdi1/Pic1 is a tumor suppressor protein. Expression of p21WAF1 is induced by wild type, but not mutant, p53 suppressor protein. The p21WAF1 protein binds to cyclin/CDK complexes and inhibits their kinase activity thereby stopping cell cycle progression. It also binds to PCNA (proliferating cell nuclear antigen) and blocks DNA replication but not the DNA repair process.Host Species: Mouse
Clone: DCS-60.2
Isotype: IgG2a
Species Reactivity: Human. Does not react with mouse and rat. Others not known
Epitope: Not determined
Immunogen: Full-length human recombinant p21 protein
Molecular Weight: 21kDa
Positive Control: Ls174T or Raji cells, Colon CA
Cellular Localization: Nuclear
Recommended for:
- Immunohistochemistry (Formalin/paraffin)
- Western Blotting (Not suitable)
- Immunofluorescence
- Immunoprecipitation (Native and denatured)
- Flow Cytometry (Not suitable)
Specifications
| p21WAF1 Ab-3 | |
| Monoclonal | |
| 1mg/mL | |
| Ab without BSA/Azide (Frozen) | |
| Full length human recombinant p21 protein | |
| IVD | |
| Primary | |
| Concentrated |
| Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation | |
| DCS-60.2 | |
| Unconjugated | |
| Mouse | |
| 200 μL | |
| Cancer and Tumor Biology | |
| Human | |
| IgG2a |
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