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p21WAF1Ab-3 Mouse Monoclonal Antibody, Epredia™

Achieve accurate, reproducible results with the Epredia™ p21WAF1 Ab-3, Mouse Monoclonal Antibody.

Manufacturer:  Epredia MS230PABX

Catalog No. MS230PABX


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Description

Description

p21WAF1/Cip1/Sdi1/Pic1 is a tumor suppressor protein. Expression of p21WAF1 is induced by wild type, but not mutant, p53 suppressor protein. The p21WAF1 protein binds to cyclin/CDK complexes and inhibits their kinase activity thereby stopping cell cycle progression. It also binds to PCNA (proliferating cell nuclear antigen) and blocks DNA replication but not the DNA repair process.

Host Species: Mouse

Clone: DCS-60.2

Isotype: IgG2a

Species Reactivity: Human. Does not react with mouse and rat. Others not known

Epitope: Not determined

Immunogen: Full-length human recombinant p21 protein

Molecular Weight: 21kDa

Positive Control: Ls174T or Raji cells, Colon CA

Cellular Localization: Nuclear

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting (Not suitable)
  • Immunofluorescence
  • Immunoprecipitation (Native and denatured)
  • Flow Cytometry (Not suitable)
Specifications

Specifications

p21WAF1 Ab-3
Monoclonal
1mg/mL
Ab without BSA/Azide (Frozen)
Full length human recombinant p21 protein
IVD
Primary
Concentrated
Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation
DCS-60.2
Unconjugated
Mouse
200 μL
Cancer and Tumor Biology
Human
IgG2a
SDS
Documents
Product Certifications
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