p53 Ab-8 Mouse Monoclonal Antibody, Epredia™

Deliver accurate, reproducible results with the Epredia™ p53 Ab-8, Mouse Monoclonal Antibody.

Supplier:  Epredia MS738P

Catalog No. MS738P

Description

p53 is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis. It binds to mdm2, SV40 T antigen and human papilloma virus E6 protein p53 senses DNA damage and possibly facilitating repair. Mutation involving p53 is found in a wide variety of malignant tumors, including breast, ovarian, bladder, colon, lung, and melanoma.

Host Species: Mouse

Clone: DO-7 + BP53-12

Isotype: IgG2b + IgG2a

Species Reactivity: Human. Others not known.

Epitope: aa 37-45 and aa 20-25

Immunogen: Recombinant human p53 protein

Molecular Weight: 53kDa

Positive Control: MDA-231, SKBR-3 cells or Colon CA

Cellular Localization: Nuclear

Recommended for:

• Immunohistochemistry (Formalin/paraffin)
• Western Blotting
• Immunoprecipitation (Native and denatured)

Specifications

• Antigen: p53 Ab-8
• Classification: Monoclonal
• Concentration: 200μg/mL
• Host Species: Mouse
• Quantity: 1 mL
• Research Discipline: Cancer and Tumor Biology
• Target Species: Human
• Isotype: IgG2a, IgG2b

• Applications: Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Clone: DO-7 + BP53-12
• Conjugate: Unconjugated
• Immunogen: Recombinant human p53 protein
• Regulatory Status: IVD
• Primary or Secondary: Primary
• Form: Concentrated