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Epredia™ Lab Vision™ Paxillin Ab-1 Mouse Monoclonal Antibody, 200µg/mL, BSA and azide

Provide accurate, reproducible results with the Epredia™ Paxillin Ab-1, Mouse Monoclonal Antibody.

Manufacturer:  Epredia™ MS404R1

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Catalog No. MS404R1

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

Paxillin is a focal adhesion protein and a substrate for several tyrosine kinases such as src, FAK, and p210BRC/ABL. The tyrosine phosphorylation of paxillin is affected by conditions that change cell-cell adhesion. Paxillin associates tightly with FAK and Crk through its SH2 domain. This interaction is independent of the extracellular matrix. Although paxillin was initially discovered in fibroblasts, its phosphorylation may also be important during neurite extension during differentiation.

Host Species: Mouse

Clone: 5H11

Isotype: IgG1/κ

Species Reactivity: Human and Rat. Others not known.

Epitope: Not determined

Immunogen: Purified recombinant full-length human paxillin protein

Molecular Weight: 68kDa

Positive Control: HeLa cells, Colon CA

Cellular Localization: Membrane and cytoplasmic

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunofluorescence
  • Immunoprecipitation (Native verified)

Note:

USA: RUO; Int'l: RUO

Specifications

Specifications

Paxillin Ab-1
Monoclonal
Unconjugated
Murine
1 mL
Cytoskeletal Protein
Human, Rat
IgG2a κ
Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
5H11
Ready-to-use for IHC (UVLP)
Purified recombinant full-length human paxillin protein
RUO
Primary
Prediluted
SDS
Documents
Product Certifications
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