PDGFRα Ab-1 Rabbit Polyclonal Antibody, Epredia™

Provide accurate, reproducible results with the Epredia™ PDGFRα Ab-1, Rabbit Polyclonal Antibody.

Supplier:  Epredia RB1691P0

Catalog No. RB1691P0

Description

PDGFR (Platelet Derived Growth Factor Receptor) exhibits two different isoforms, α and ß coded by two different genes. They possess five immunoglobulin like domains that are involved in ligand binding. Two tyrosine kinase domains are separated by a kinase insert to which PI-3 kinase can bind. PDGF AA can bind autophosphorylate and activate only PDGFR, alpha while PDGF BB can bind and activate to both PDGFR, α and β

Host Species: Rabbit

Isotype: IgG

Species Reactivity: Human, Mouse, and Rat. Others not known.

Epitope: C-terminal

Immunogen: A synthetic peptide derived from the C-terminus of the precursor form of human PDGFRα

Molecular Weight: ∽190kDa

Postitive Control: Ovarian CA

Cellular Localization: Membrane Specific for PDGFR, α and does not react with PDGFR, β.

Recommended for:

• Immunohistochemistry

Note:

USA: RUO; Int'l: RUO

Specifications

• Antigen: PDGFR, alpha Ab-1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Immunogen: A synthetic peptide derived from the C-terminus of the precursor form of human PDGFR, alpha
• Quantity: 100 μL
• Research Discipline: Growth Factor
• Target Species: Human, Mouse
• Isotype: IgG

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 1mg/mL
• Host Species: Rabbit
• Purification Method: Purified with BSA and azide
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Form: Concentrated