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PDGFRα Ab-1 Rabbit Polyclonal Antibody, Epredia™
Provide accurate, reproducible results with the Epredia™ PDGFRα Ab-1, Rabbit Polyclonal Antibody.
Supplier: Epredia RB1691P1ABX
Description
PDGFR (Platelet Derived Growth Factor Receptor) exhibits two different isoforms, α and ß coded by two different genes. They possess five immunoglobulin like domains that are involved in ligand binding. Two tyrosine kinase domains are separated by a kinase insert to which PI-3 kinase can bind. PDGF AA can bind autophosphorylate and activate only PDGFR, alpha while PDGF BB can bind and activate to both PDGFR, α and βHost Species: Rabbit
Isotype: IgG
Species Reactivity: Human, Mouse, and Rat. Others not known.
Epitope: C-terminal
Immunogen: A synthetic peptide derived from the C-terminus of the precursor form of human PDGFRα
Molecular Weight: ∽190kDa
Postitive Control: Ovarian CA
Cellular Localization: Membrane Specific for PDGFR, α and does not react with PDGFR, β.
Recommended for:
- Immunohistochemistry
Note:
USA: RUO; Int'l: RUO
Specifications
PDGFR, alpha Ab-1 | |
Polyclonal | |
Unconjugated | |
A synthetic peptide derived from the C-terminus of the precursor form of human PDGFR, alpha | |
500 μL | |
Growth Factor | |
Human, Mouse | |
IgG |
Immunohistochemistry (Paraffin) | |
1mg/mL | |
Rabbit | |
Purified without BSA and azide | |
RUO | |
Primary | |
Concentrated |
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