ROC1 Ab-1 Rabbit Polyclonal Antibody, Epredia™

Provide accurate, reproducible results with the Epredia™ ROC1 Ab-1, Rabbit Polyclonal Antibody.

Supplier:  Epredia RB069P0

Catalog No. RB069P0

Description

ROC1 and ROC2 are the two highly conserved RING finger proteins that are homologous to APC11, a subunit of the anaphase-promoting complex(APC). ROC1 and ROC2 commonly interact with all cullins while APC11 specifically interacts with APC2, a cullin-related APC subunit. ROC1 and APC11 immunocomplexes can catalyze isopeptide ligations to form polyubiquitin chains in an E1- and E2-dependent manner. ROC1 is thought to play a unique role in the ubiquitination reaction by heterodimerizing with cullin1 to catalyze ubiquitin polymerization.

Host Species: Rabbit

Isotype: IgG

Species Reactivity: Human and Mouse. Others not known.

Epitope: aa 97-108

Immunogen: A peptide corresponding to amino acid residue 97-108 (CPLDNREWEFQKYGH) from C-terminus of the human ROC1

Molecular Weight: 13kDa

Positive Control: HeLa cells

Cellular Localization: Nuclear

Recommended for:

• Western Blotting
• Immunoprecipitation (Native verified)

Note:

USA: RUO; Int'l: RUO

Specifications

• Antigen: ROC1 Ab-1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Immunogen: A peptide corresponding to amino acid residue 97-108 (CPLDNREWEFQKYGH) from C-terminus of the human ROC1
• Quantity: 100 μL
• Research Discipline: Cell Cycle
• Target Species: Human
• Isotype: IgG

• Applications: Western Blot
• Concentration: 1mg/mL
• Host Species: Rabbit
• Purification Method: Purified with BSA and azide
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Form: Concentrated