TAG-72/CA 72-4TM Ab-1 Mouse Monoclonal Antibody, Epredia™
Provide accurate, reproducible results with the Epredia™ TAG-72/CA 72-4 Ab-1, Mouse Monoclonal Antibody.
Manufacturer: Epredia MS138PABX
Tumor-associated glycoprotein (TAG-72) is an oncofetal antigen with properties of a mucin. About 60% of carcinoma patients express TAG-72 in their sera.
Host Species: Mouse
Species Reactivity: Human, Cow, Dog, Hamster and Rat. Others not known.
Epitope: Mucin-carried-sialylated-Tn epitope
Immunogen: Membrane-enriched fraction of a human breast carcinoma liver metastasis
Molecular Weight: >1000kDa
Positive Control: Breast or lung CA
Cellular Localization: Cell surface and cytoplasmic. The majority of human adenocarcinomas including colorectal, pancreatic, gastric, ovarian, endometrial, mammary, and non-small cell lung cancer display some cell populations that are positive for Ab-1 staining. Weak or no reactivity has been observed with most cell types of normal adult tissue excepting the secretory endometrium. Ab-1 is reportedly useful in distinguishing pulmonary adenocarcinomas (B72.3+) from pleural mesotheliomas (B72.3-).
- Immunohistochemistry (Formalin/paraffin)
- Flow Cytometry
USA: RUO; Int'l: RUO
|TAG-72/CA 72-4 Ab-1|
|Cancer and Tumor Biology|
|Bovine, Canine, Hamster, Human, Rat|
|Flow Cytometry, Immunohistochemistry (Paraffin)|
|Membrane-enriched fraction of a human breast carcinoma liver metastasis|
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