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TIMP-1 Ab-2 Mouse Monoclonal Antibody, Epredia™

Provide accurate, reproducible results with the Epredia™ TIMP-1 Ab-2, Mouse Monoclonal Antibody.

Manufacturer:  Epredia MS608R7

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Catalog No. MS608R7

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

Tissue inhibitor of metalloproteinases-1 (TIMP-1) and Tissue inhibitor of metalloproteinases-2 (TIMP-2) are inhibitory enzymes of matrix metalloproteinase family, and are thought to be of great importance in the maintenance of connective tissue integrity. TIMP-1 forms a complex of 1:1 stoichiometry with activated interstitial collagenase, activated stromelysin, active form of 72kDa Type IV collagenase (also known as MMP-2 or gelatinase A), and latent and active forms 92kDa Type IV collagenase (also known as MMP-9 or gelatinase B). TIMPs inhibit the proteolytic invasiveness of tumor cells and normal placental trophoblast cells.

Host Species: Mouse

Clone: 102D1

Isotype: IgG1

Species Reactivity: Human. Others not known.

Epitope: Not determined

Immunogen: Recombinant human TIMP-1

Molecular Weight: 28.5kDa

Positive Control: Conditioned, serum-free medium from (TPA-treated) human fetal lung cell line HFL-1; Bladder, breast and ovarian CA

Cellular Localization: Cytoplasmic

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting

Note:

USA: RUO; Int'l: RUO

Specifications

Specifications

TIMP-1 Ab-2
Monoclonal
Unconjugated
Mouse
7 mL
Proteases And Inhibitors
Human
IgG1
Immunohistochemistry (Paraffin), Western Blot
102D1
Ready-to-use for IHC (UVLP)
Recombinant human TIMP-1
RUO
Primary
Prediluted
SDS
Documents
Product Certifications
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