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TIMP-2 Ab-5 Mouse Monoclonal Antibody, Epredia™

Provide accurate, reproducible results with the Epredia™ TIMP-2 Ab-5, Mouse Monoclonal Antibody.

Manufacturer:  Epredia MS1485R7

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Catalog No. MS1485R7

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

TIMP-1 and TIMP-2 are inhibitory enzymes of matrix metalloproteinase family, and are thought to be of great importance in the maintenance of connective tissue integrity. TIMP-2 shows the highest binding affinity to both the latent (pro) and active forms of 72kDa Type IV collagenase (also known as MMP-2 or gelatinase A). It also has affinity for the active form of 92kDa Type IV collagenase (also known as MMP-9 or gelatinase B). TIMP-2 inhibits the proteolytic invasiveness of tumor cells and normal placental trophoblast cells.

Host Species: Mouse

Clone: 3A4

Isotype: IgG2a/κ

Species Reactivity: Human, Mouse, Rat, Rabbit, Cow and Guinea Ppig. Others not known.

Epitope: N-terminal

Immunogen: A synthetic peptide from the N-terminal region of human TIMP-2 protein

Molecular Weight: 21kDa

Positive Control: Conditioned, serum-free medium from (TPA-treated) HFL-1 cells; Pancreatic or colon CA

Cellular Localization: Cytoplasmic

Recommended for:

  • Immunohistochemistry (Formalin/paraffin only)
  • Western Blotting
  • Immunoprecipitation (Not suitable)

Note:

USA: RUO; Int'l: RUO

Specifications

Specifications

TIMP-2 Ab-5
Monoclonal
Unconjugated
Mouse
7 mL
Proteases And Inhibitors
Bovine, Guinea Pig, Human, Murine, Rabbit, Rat
IgG2a κ
Immunohistochemistry (Paraffin), Western Blot
3A4
Ready-to-use for IHC (UVLP)
A synthetic peptide from the N-terminal region of human TIMP-2 protein
RUO
Primary
Prediluted
SDS
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