Vascular Endothelial Growth Factor (VEGF) Ab-3 Mouse Monoclonal Antibody, Epredia™

Provide accurate, reproducible results with the Epredia™ Vascular Endothelial Growth Factor (VEGF) Ab-3, Mouse Monoclonal Antibody.

Supplier:  Epredia MS350P1ABX

Catalog No. MS350P1ABX

Description

VEGF (vascular endothelial growth factor) is a homodimeric, disulfide-linked glycoprotein involved in angiogenesis which promotes tumor progression and metastasis. It exhibits potent mitogenic and permeability inducing properties specific for the vascular endothelium. Of the four isoforms of VEGF, the smaller two, VEGF165 and VEGF121, are secreted proteins and act as diffusible agents, whereas the larger two (VEGF189 and VEGF206) remain cell associated.

Host Species: Mouse

Clone: JH121

Isotype: IgG1/κ

Species Reactivity: Human and Rabbit. Others not known.

Epitope: Not determined

Immunogen: Recombinant human VEGF₁₂₁

Molecular Weight: 19-22kDa (reduced)

Positive Control: VEGF₁₆₅ recombinant protein, Angiosarcoma

Cellular Localization: Cytoplasmic, cell surface and extracellular matrix Ab-3 is excellent for neutralizing the bioactivity of human VEGF.

Recommended for:

• Neutralizes Bioactivity of VEGF

Note:

USA: RUO; Int'l: RUO

Specifications

• Antigen: Vascular Endothelial Growth Factor (VEGF) Ab-3
• Classification: Monoclonal
• Concentration: 1mg/mL
• Host Species: Mouse
• Quantity: 100 μL
• Research Discipline: Angiogenesis
• Target Species: Human, Rabbit
• Isotype: IgG2a κ

• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Clone: JH121
• Conjugate: Unconjugated
• Immunogen: Recombinant human VEGFsubscript121subscript
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Form: Concentrated