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  5. Tocris Bioscience™ Lalistat 1

Tocris Bioscience™ Lalistat 1
GREENER_CHOICE

Catalog No. 609850
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Potent and selective lysosomal acid lipase (LAL) inhibitor

Lalistat 1 is a potent and selective lysosomal acid lipase (LAL) inhibitor (IC50 = 68 nM). Exhibits no significant activity against pancreatic lipase or lipoprotein lipase at 10 μM concentration. Blocks LAL-mediated lipid hydrolysis of acetylated LDL and reduces efflux of cholesterol from lipid-loaded cells resulting in increased cellular cholesterol ester levels.

Specifications

Chemical Name or Material 4-(Piperidin-1-yl)-1,2,5-thiadiazol-3-yl morpholine-4-carboxylate
CAS 501104-16-1
Assay Percent Range >98%
Quantity 50 mg
Molecular Formula C12H18N4O3S
Formula Weight Observed MW: 298.36
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