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Lambda Light Chain Mouse anti-Human, Alexa Fluor™ 532, Clone: ICO106, Novus Biologicals™

Mouse Monoclonal Antibody

Manufacturer:  Novus BiologicalsSupplier Diversity Partner NBP233308AF532

Catalog No. NP233308A32


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Description

Description

Lambda Light Chain Monoclonal antibody specifically detects Lambda Light Chain in Human samples. It is validated for Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen).
Specifications

Specifications

Lambda Light Chain
ICO106
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
Conjugated, Purified
IGLC1
Human IgG was used as immunogen to generate the Lambda antibody.
Protein G purified
Adaptive Immunity, Immunology
Primary
3537.0
Human
ELISA, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry (Paraffin), Western Blot
Alexa Fluor™ 532
50 mM sodium borate with 0.05% sodium azide
IGLC, immunoglobulin lambda constant group
Mouse
IgG1 Kappa
0.1 mL
Store at 4°C in the dark.
Monoclonal
This MAb is specific to lambda light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the lambda light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin′s lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.
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