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Laminin alpha-2 Mouse anti-Human, Mouse, Rat, Clone: CL3450, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA524656

Catalog No. PIMA524656


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Description

Description

Immunogen sequence: DKLKPIKELE DNLKKNISEI KELINQARKQ ANSIKVSVSS GGDCIRTYKP EIKKGSYNNI VVNVKTAVAD NLLFYLGSAK FIDFLAIEMR KGKVSFLWDV GSGVGRVEYP DLTIDDSYWY RIVASRTGRN GT Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 98%. Binds to an epitope located within the peptide sequence DKLKPIKELEDNLKK as determined by overlapping synthetic peptides.

Laminin, an extracellular protein, is a major component of the basement membrane. It is thought to mediate the attachment, migration, and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. It is composed of three subunits, alpha, beta, and gamma, which are bound to each other by disulfide bonds into a cross-shaped molecule. This gene encodes the alpha 2 chain, which constitutes one of the subunits of laminin 2 (merosin) and laminin 4 (s-merosin). Mutations in this gene have been identified as the cause of congenital merosin-deficient muscular dystrophy. Two transcript variants encoding different proteins have been found for this gene.
Specifications

Specifications

Laminin alpha-2
Monoclonal
1.0 mg/mL
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
P24043, Q60675
LAMM, laminin M, laminin alpha-2, merosin heavy chain,
Mouse
IgG1
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
16773, 309368, 3908
Immunohistochemistry, Western Blot
CL3450
Unconjugated
LAMA2
Liquid
LAMA2
Recombit protein corresponding to Human Laminin alpha-2
Protein A
RUO
Antibody
Monoclonal
Human, Mouse, Rat
Documents
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