Laminin alpha-3 Mouse anti-Human, Clone: CL3112, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA524648
Immunogen sequence: LLNRIRTWQK THQGENNGLA NSIRDSLNEY EAKLSDLRAR LQEAAAQAKQ ANGLNQENER ALGAIQRQVK EINSLQSDFT KYLTTADSSL LQTNIALQLM EKSQKEYE Highest antigen sequence identity to the following orthologs: Mouse - 74%, Rat - 71%. Binds to an epitope located within the peptide sequence EINSLQSDFT as determined by overlapping synthetic peptides.The protein encoded by this gene belongs to the laminin family of secreted molecules. Laminins are heterotrimeric molecules that consist of alpha, beta, and gamma subunits that assemble through a coiled-coil domain. Laminins are essential for formation and function of the basement membrane and have additional functions in regulating cell migration and mechanical signal transduction. This gene encodes an alpha subunit and is responsive to several epithelial-mesenchymal regulators including keratinocyte growth factor, epidermal growth factor and insulin-like growth factor. Mutations in this gene have been identified as the cause of Herlitz type junctional epidermolysis bullosa and laryngoonychocutaneous syndrome. Alternative splicing and alternative promoter usage result in multiple transcript variants. [provided by RefSeq, Dec 2014].
|PBS with 40% glycerol and 0.02% sodium azide; pH 7.2|
|Epiligrin, LAMA3, Laminin-5|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Immunohistochemistry, Western Blot|
|Recombit protein corresponding to Human Laminin alpha-3|
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