Laminin alpha-5 Mouse anti-Human, Clone: CL3118, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA524649
Immunogen sequence: LNLSSIILDV NQDRLTQRAI EASNAYSRIL QAVQAAEDAA GQALQQADHT WATVVRQGLV DRAQQLLANS TALEEAMLQE QQRLGLVWAA L Binds to an epitope located within the peptide sequence RQGLVDRAQQ as determined by overlapping synthetic peptides.Components of the extracellular matrix exert myriad effects on tissues throughout the body. In particular, the laminins, a family of heterotrimeric extracellular glycoproteins, affect tissue development and integrity in such diverse organs as the kidney, lung, skin, and nervous system. It is thought that laminins mediate the attachment, migration, and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Laminins function as heterotrimeric complexes of alpha, beta, and gamma chains, with each chain type representing a different subfamily of proteins. The protein encoded by this gene belongs to the alpha subfamily of laminin chains and is a major component of basement membranes. Two transcript variants encoding different isoforms have been found for this gene, but the full-length nature of one of them has not been determined.
|PBS with 40% glycerol and 0.02% sodium azide; pH 7.2|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Immunohistochemistry, Western Blot|
|Recombit protein corresponding to Human Laminin alpha-5|
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