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Thermo Scientific™ Lab Vision™ Laminin B2/γ 1 Ab-1, Rat Monoclonal Antibody

Recommended for Immunohistochemistry (Acetone-fixed frozen and acid-alcohol-fixed, paraffin-embedded), Immunofluorescence and Immunoprecipitation (Native and denatured), Thermo Scientific™ Laminin B2/γ1 Ab-1, Rat Monoclonal Antibody provides accurate, reproducible results.

Manufacturer:  Thermo Scientific™ RT795B1

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Catalog No. RT795B1


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Description

Description

Recommended for Immunohistochemistry (Acetone-fixed frozen and acid-alcohol-fixed, paraffin-embedded), Immunofluorescence and Immunoprecipitation (Native and denatured), Thermo Scientific™ Laminin B2/γ1 Ab-1, Rat Monoclonal Antibody provides accurate, reproducible results.

Laminins are large heterotrimeric, noncollagenous glycoproteins composed of α, β, and γ chains. They are ubiquitously present in basement membrane (BM) along with entactin/nidogen (EN), collagen type IV (CIV), and large heparan sulfate proteoglycan (HSPG), which interact specifically with each other to form a continuous and regular BM. Alterations of BM integrity, from local discontinuities up to complete loss, are described in many types of human and animal epithelial neoplasms.

Host Species: Rat

Clone: A5

Isotype: IgG2a/κ

Species Reactivity: Human and Mouse. Others not known.

Epitope: Not determined

Immunogen: Murine EHS laminin preparation

Molecular Weight: ~210kDa

Positive Control: LS174T cells, Normal colon or colon CA

Cellular Localization: Basement membrane Specificity of Ab-1 was established by immunoprecipitation and immunofluorescence of human skeletal muscle and kidney with laminin chain-specific MAbs. Ab-1 stains uniformly all human and murine basement membranes.

Recommended for:

  • Immunohistochemistry (Acetone-fixed frozen and acid-alcohol-fixed, paraffin-embedded)
  • Immunofluorescence
  • Immunoprecipitation (Native and denatured)

Note:

USA: RUO; Int'l: RUO

Specifications

Specifications

Laminin B2/gamma1 Ab-1
Monoclonal
200µg/mL
Concentrated
Murine EHS laminin preparation
500μL
Extracellular Matrix
Primary
Human
Immunohistochemistry (Frozen), Immunoprecipitation
A5
Biotin
Rat
IgG2a kappa
RUO
Primary
Monoclonal
SDS
Documents
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