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Laminin B2/γ1 Ab-1 Rat Monoclonal Antibody, Epredia™
Recommended for Immunohistochemistry (Acetone-fixed frozen and acid-alcohol-fixed, paraffin-embedded), Immunofluorescence and Immunoprecipitation (Native and denatured), Epredia™ Laminin B2/γ1 Ab-1, Rat Monoclonal Antibody provides accurate, reproducible results.
Supplier: Epredia RT795P0
Description
Laminins are large heterotrimeric, noncollagenous glycoproteins composed of α, β, and γ chains. They are ubiquitously present in basement membrane (BM) along with entactin/nidogen (EN), collagen type IV (CIV), and large heparan sulfate proteoglycan (HSPG), which interact specifically with each other to form a continuous and regular BM. Alterations of BM integrity, from local discontinuities up to complete loss, are described in many types of human and animal epithelial neoplasms.Host Species: Rat
Clone: A5
Isotype: IgG2a/κ
Species Reactivity: Human and Mouse. Others not known.
Epitope: Not determined
Immunogen: Murine EHS laminin preparation
Molecular Weight: ∽210kDa
Positive Control: LS174T cells, Normal colon or colon CA
Cellular Localization: Basement membrane Specificity of Ab-1 was established by immunoprecipitation and immunofluorescence of human skeletal muscle and kidney with laminin chain-specific MAbs. Ab-1 stains uniformly all human and murine basement membranes.
Recommended for:
- Immunohistochemistry (Acetone-fixed frozen and acid-alcohol-fixed, paraffin-embedded)
- Immunofluorescence
- Immunoprecipitation (Native and denatured)
Note:
USA: RUO; Int'l: RUO
Specifications
Laminin B2/gamma1 Ab-1 | |
Monoclonal | |
200µg/mL | |
Rat | |
100 μL | |
Extracellular Matrix | |
Human | |
IgG2a κ |
Immunohistochemistry (Frozen), Immunoprecipitation | |
A5 | |
Unconjugated | |
Murine EHS laminin preparation | |
RUO | |
Primary | |
Concentrated |
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