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LanthaScreen™ Tb-peIF2a (pSer52) Antibody Kit
LanthaScreen™ Tb-peIF2a (pSer52) Antibody Kit
Supplier: LIFE TECHNOLOGIES PV4810
Description
The alpha subunit of Eukaryotic initiation factor 2 (eIF2alpha) plays a key regulatory role in protein synthesis. In response to a cellular stress, phosphorylation of eIF2alpha at Ser52 occurs by the EIF2AK family of kinases including PERK (EIF2AK3) and PKR (EIF2AK2) to prohibit the initiation of protein synthesis.For use in combination with the GFP-EIF2alpha physiological protein substrate (PV4809) to evaluate inhibitors in medium to high throughput screening applications.
Specifications
| Serine/threonine kinase | |
| Tb (Terbium)/GFP (EmGFP) | |
| 25 μg | |
| Kinase Activity | |
| 9833 | |
| Terbium-labeled anti-eIF2alpha [pSer52] antibody in HEPES buffered saline. Store at -20°C. | |
| Biochemical terbium phospho-specific activity | |
| 340⁄490, 520 | |
| Dry Ice | |
| Hu | |
| Serine⁄Threonine Kinases | |
| EIF2AK2, EIF2AK3 |
| Kinase Assay, Enzyme and Protein Activity Assays, Kinase Assay, Protein Assay | |
| HPK38, KIAA017 | |
| RUO | |
| Primary | |
| 1 Each | |
| 150000 Da | |
| 384-well Plate | |
| Human | |
| End Point | |
| EIF2AK1, EIF2AK2, EIF2AK3 | |
| TR-FRET | |
| LanthaScreen™ |
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Product Title
For Research Use Only. Not for use in diagnostic procedures.
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