DescriptionA phospho specific antibody directed to the ezrin⁄radixin⁄moesin (ERM) peptide that is a substrate for LRRK2 (Leucine-rich repeat kinase 2) and LRRK2 mutants. Mutations in LRRK2 have been found to be related to late-onset Parkinson's disease.
For use in combination with the Fluorescein-ERM (LRRKtide) substrate (PV4901) to evaluate inhibitors in medium to high throughput screening applications.
|Biochemical Kinase Assays, Drug Discovery and Development, Kinase Biology, Pharma and Biopharma, Target and Lead Identification and Validation|
|Tb (Terbium), lanthanide chelates|
|RUO, For research use only|
For Research Use Only. Not for use in diagnostic procedures.
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