LAT Mouse anti-Human, Clone: LAT.10-17 (10-17), Abnova™
Mouse monoclonal antibody raised against human LAT.
Manufacturer: Abnova Corporation MAB12621
The protein encoded by this gene is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain-containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling complexes located near the site of TCR engagement. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq]
|Mouse monoclonal antibody raised against human LAT.|
|In PBS, pH 7.2 (0.09% sodium azide).|
|Store at 4°C.
Aliquot to avoid repeated freezing and thawing.
|Immunohistochemistry (PFA fixed), Immunoprecipitation, Western Blot|
|Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (20 ug/mL) Immunoprecipitation Western Blot The optimal working dilution should be determined by the end user.|
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