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LAT Mouse anti-Human, Clone: LAT.10-17 (10-17), Abnova™

Mouse monoclonal antibody raised against human LAT.

Manufacturer:  Abnova Corporation MAB12621

Catalog No. 89-934-457


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Description

Description

The protein encoded by this gene is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain-containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling complexes located near the site of TCR engagement. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq]

Specifications

Specifications

LAT
LAT.10-17 (10-17)
Mouse monoclonal antibody raised against human LAT.
In PBS, pH 7.2 (0.09% sodium azide).
LAT1/pp36
Mouse
IgG1, kappa
50 ug
Store at 4°C.
Aliquot to avoid repeated freezing and thawing.
Monoclonal
Human
Immunohistochemistry (PFA fixed), Immunoprecipitation, Western Blot
Unconjugated
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (20 ug/mL) Immunoprecipitation Western Blot The optimal working dilution should be determined by the end user.
Liquid
LAT
Human LAT
Affinity purification
RUO
Primary
27040
SDS
Documents
Product Certifications
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