LCK Mouse anti-Human, Clone: 33D196, Abnova™
Mouse monoclonal antibody raised against synthetic peptide of human LCK.
Manufacturer: Abnova Corporation MAB12964
This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants, encoding the same protein, have been described. [provided by RefSeq]
|Mouse monoclonal antibody raised against synthetic peptide of human LCK.|
|In PBS (0.02% sodium azide).|
|Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
|Immunohistochemistry (PFA fixed), Western Blot|
|Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (5 ug/mL) Western Blot (1:500-1:1000) The optimal working dilution should be determined by the end user.|
|A synthetic peptide corresponding to human LCK.|
|Protein G purification|
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