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LDHB Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 199881AP

Catalog No. 50-173-2639


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Description

Description

The antibody has no cross reaction with LDHA and LDHC.

Lactate dehydrogenase (LDH) is the enzyme in the glycolytic pathway that converts pyruvate to lactate with concomitant interconversion of NADH and NAD+. In mammals, the enzyme is encoded by three genes: LDHA (M or muscle form), LDHB (H or heart form), and LDHC (X or testis form). The three human LDHs have 84-89% sequence similarities and 69-75% amino acid identities. There are five different LDH isoenzymes based on the proportion of M and H chains existing in the LDH tetrameric structure. The LDHA is hypoxia inducible and its expression is directly controlled by the transcriptional activity of the hypoxia inducible factor 1a (HIF1a). LDHB is also known to be upregulated in many cancers.
Specifications

Specifications

LDHB
0.23 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P07195, P16125, P42123
lactate dehydrogenase B, LDH B, LDH H, LDH heart subunit, LDHB, TRG 5
Rabbit
IgG
150 μL
-20°C
Primary
16832, 24534, 3945
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Unconjugated
LDHB
Liquid
Ldhb
Peptide
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
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