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Tocris Bioscience™ LDN 212854

Potent bone morphogenetic protein type I (ALK) inhibitor

$206.50 - $865.50

Specifications

CAS 1432597-26-6
Formula Weight 406.48g/mol
Molecular Formula 25H22N6
Solubility Soluble to 50 mM in 2eq.HCl
Storage Requirements Store at −20°C
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
61-511-0 View Documents Tocris Bioscience™
6151/10
10mg Each for $206.50
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61-515-0 View Documents Tocris Bioscience™
6151/50
50mg Each for $865.50
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Description

Description

Potent ALK inhibitor (IC50 values are 1.3, 2.4, 85.8, 2,133 and 9,276 nM for ALK2, ALK1, ALK3, ALK4 and ALK5, respectively). Exhibits selectivity for ALK2 over ALK4 and ALK5 in cellular assays. Inhibits heterotopic ossification in a mutant ALK2 mouse model of fibrodysplasia ossificans progressiva. Also exhibits activity against RIPK2, ABL1 and PDGFR-β (IC50 values < 100 nM).
Specifications

Specifications

1432597-26-6
25H22N6
Store at −20°C
406.48g/mol
Soluble to 50 mM in 2eq.HCl
Yellow

For Research Use Only

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