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  8. LH 846, Tocris Bioscience™

LH 846, Tocris Bioscience™

Catalog Number 489610
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
639052-78-1
C16H13ClN2OS
316.80
MFCD03786038
DYHAMRNAHTWYKY-UHFFFAOYSA-N
n-5-chloro-6-methyl-1,3-benzothiazol-2-yl-2-phenylacetamide, benzeneacetamide, n-5-chloro-6-methyl-2-benzothiazolyl, n-5-chloro-6-methyl-2-benzothiazolyl benzeneacetamide, n-5-chloro-6-methylbenzothiazol-2-yl-2-phenylacetamide, n-5-chloro-6-methyl-benzothiazol-2-yl-2-phenyl-acetamide, n-5-chloro-6-methylbenzo d thiazol-2-yl-2-phenylacetamide
851474
N-(5-chloro-6-methyl-1,3-benzothiazol-2-yl)-2-phenylacetamide
CC1=C(Cl)C=C2N=C(NC(=O)CC3=CC=CC=C3)SC2=C1
This item is not returnable. View return policy
639052-78-1
C16H13ClN2OS
316.80
MFCD03786038
DYHAMRNAHTWYKY-UHFFFAOYSA-N
n-5-chloro-6-methyl-1,3-benzothiazol-2-yl-2-phenylacetamide, benzeneacetamide, n-5-chloro-6-methyl-2-benzothiazolyl, n-5-chloro-6-methyl-2-benzothiazolyl benzeneacetamide, n-5-chloro-6-methylbenzothiazol-2-yl-2-phenylacetamide, n-5-chloro-6-methyl-benzothiazol-2-yl-2-phenyl-acetamide, n-5-chloro-6-methylbenzo d thiazol-2-yl-2-phenylacetamide
851474
N-(5-chloro-6-methyl-1,3-benzothiazol-2-yl)-2-phenylacetamide
CC1=C(Cl)C=C2N=C(NC(=O)CC3=CC=CC=C3)SC2=C1

Description

Selective casein kinase 1δ inhibitor

Selective inhibitor of casein kinase (CK) 1δ (IC50 values are 290 nM, 1.3 μM and 2.5 μM for CK1δ, ε and α); displays no inhibitory activity at CK2. Inhibits CK1δ-dependent phosphorylation and degradation of PER1 protein. Shown to lengthen the circadian period in U2OS cells, with minimal effect on amplitude.
Quantity 10 mg
Formula Weight 316.81
Percent Purity >98%
Chemical Name or Material LH 846

Safety and Handling

Recommended Storage Store at +4°C
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