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LIFR Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA550514

Catalog No. PA550514


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Description

Description

The antibody detects endogenous levels of total LIF Receptor alpha protein.

This gene encodes a protein that belongs to the type I cytokine receptor family. This protein combines with a high-affinity converter subunit, gp130, to form a receptor complex that mediates the action of the leukemia inhibitory factor, a polyfunctional cytokine that is involved in cellular differentiation, proliferation and survival in the adult and the embryo. Mutations in this gene cause Schwartz-Jampel syndrome type 2, a disease belonging to the group of the bent-bone dysplasias. A translocation that involves the promoter of this gene, t(5;8)(p13;q12) with the pleiomorphic adenoma gene 1, is associated with salivary gland pleiomorphic adenoma, a common type of benign epithelial tumor of the salivary gland. Multiple splice variants encoding the same protein have been found for this gene.
Specifications

Specifications

LIFR
Polyclonal
Unconjugated
LIFR
Liquid
LIFR
Synthetic peptide corresponding to a region derived from internal residues of human leukemia inhibitory factor receptor alpha
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Immunohistochemistry (Paraffin)
0.5 mg/mL
PBS with 50% glycerol and 0.05% sodium azide; pH 7.3
P42702
SWS, SJS2, STWS, CD118, LIF-R
Rabbit
IgG
100 μL
-20°C
Primary
3977
Documents
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