LIMK1 Mouse anti-Human, Clone: OTI 7C3, liquid, TrueMAB™ 

Mouse Monoclonal Antibody

Manufacturer:  OriGene TA503007

Catalog No. 50-167-3988

Description

There are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine-rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein-protein interactions. LIM kinase-1 and LIM kinase-2 belong to a small subfamily with a unique combination of 2 N-terminal LIM motifs and a C-terminal protein kinase domain. LIMK1 is likely to be a component of an intracellular signaling pathway and may be involved in brain development. LIMK1 hemizygosity is implicated in the impaired visuospatial constructive cognition of Williams syndrome.

Specifications

• Antigen: LIMK1
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: LIMK1
• Format: Liquid
• Gene Symbols: LIMK1
• Immunogen: Full length human recombit protein of human LIMK1 produced in HEK293T cell.
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Type: Antibody
• Monoclonal or Polyclonal: Monoclonal
• Target Species: Human

• Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot
• Clone: OTI 7C3
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: P53667
• Gene Alias: LIMK, LIMK-1
• Host Species: Mouse
• Isotype: IgG2b
• Quantity: 100 μL
• Storage Requirements: -20° C, Avoid Freeze/Thaw Cycles
• Primary or Secondary: Primary
• Gene ID (Entrez): 3984