LIMK1 Mouse anti-Human, Clone: OTI6A7, liquid, TrueMAB
Mouse Monoclonal Antibody
Manufacturer: OriGene TA502974
DescriptionThere are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine-rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein-protein interactions. LIM kinase-1 and LIM kinase-2 belong to a small subfamily with a unique combination of 2 N-terminal LIM motifs and a C-terminal protein kinase domain. LIMK1 is likely to be a component of an intracellular signaling pathway and may be involved in brain development. LIMK1 hemizygosity is implicated in the impaired visuospatial constructive cognition of Williams syndrome.
|Full length human recombit protein of human LIMK1 produced in HEK293 cell.|
|Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot|
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide|
|-20° C, Avoid Freeze/Thaw Cycles|
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