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LIN28B Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA550609

Catalog No. PA550609


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Description

Description

The antibody detects endogenous levels of total LIN28B protein.

The protein encoded by this gene belongs to the lin-28 family, which is characterized by the presence of a cold-shock domain and a pair of CCHC zinc finger domains. This gene is highly expressed in testis, fetal liver, placenta, and in primary human tumors and cancer cell lines. It is negatively regulated by microRNAs that target sites in the 3 ft. UTR, and overexpression of this gene in primary tumors is linked to the repression of let-7 family of microRNAs and derepression of let-7 targets, which facilitates cellular transformation. [provided by RefSeq, Jun 2012]
Specifications

Specifications

LIN28B
Polyclonal
Unconjugated
LIN28B
Liquid
LIN28B
Synthetic peptide corresponding to residues near the C terminal of human lin-28 homolog B (C. elegans)
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Western Blot
1.6 mg/mL
PBS with 50% glycerol and 0.05% sodium azide; pH 7.3
Q6ZN17, Q45KJ6
CSDD2
Rabbit
IgG
100 μL
-20°C
Primary
380669, 389421
Documents
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