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LIN7B Mouse anti-Human, Clone: OTI1F11, liquid, TrueMAB™ Non-distribution product as customer accommodation.

Mouse Monoclonal Antibody

Manufacturer:  OriGeneSupplier Diversity Partner TA501480

Catalog No. 50-167-2624


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Description

Description

Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains. The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. Ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may function in localizing synaptic vesicles at synapses where it is recruited by beta-catenin and cadherin. Required to localize Kir2 channels, GABA transporter (SLC6A12) and EGFR/ERBB1, ERBB2, ERBB3 and ERBB4 to the basolateral membrane of epithelial cells. May increase the amplitude of ACCN3 acid-evoked currents by stabilizing the channel at the cell surface.
Specifications

Specifications

LIN7B
Monoclonal
1 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Q9HAP6
LIN-7B, MALS-2, MALS2, VELI2
Mouse
IgG2b
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
64130
Flow Cytometry, Western Blot
OTI1F11
Unconjugated
LIN7B
Liquid
LIN7B
Full length human recombit protein of human LIN7B produced in HEK293T cell.
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
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