LIPG Monoclonal Antibody (LIP10-106.4), Invitrogen™

Mouse Monoclonal Antibody

Supplier:  Thermo Scientific MA110610

Catalog No. 01-671-563

Description

MA1-10610 detects Lipase from human samples. MA1-10610 has been successfully used in ELISA applications. The MA1-10610 immunogen is purified human pancreatic Lipase.

LIPG (Lipase G, Endohelial type) is an endothelial lipase which is a novel member of the lipoprotein lipase gene family. LIPG is synthesized by endothelial cells and functions at the site of synthesis. LIPG most likely plays a physiological role in modulating lipoprotein metabolism. Overexpressed LIPG has been shown to reduce HDL cholesterol levels, whereas an LIPG deficiency appears to be effective in elevating HDL cholesterol levels in animals. LIPG has substantial phospholipase activity and may be involved in lipoprotein metabolism and vascular biology. Also, LIPG is designated a member of the TG lipase family by its sequence and characteristic lid region which provides substrate specificity for enzymes of the TG lipase family. LIPG is a carboxyl esterase that hydrolyzes high density lipoproteins, emulsifies triglycerides, is essential for the efficient digestion of dietary fats and can bind to heparin.

Specifications

• Antigen: LIPG
• Classification: Monoclonal
• Concentration: ∽1 mg/mL
• Formulation: PBS with no preservative; pH 7.4
• Gene Accession No.: Q9Y5X9
• Gene Symbols: LIPG
• Immunogen: Purified human pancreatic Lipase.
• Quantity: 500 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: ELISA
• Clone: LIP10-106.4
• Conjugate: Unconjugated
• Gene: LIPG
• Gene Alias: 3110013K01Rik; EDL; EL; endothelial cell-derived lipase; Endothelial lipase; endothelial-derived lipase; lipase; lipase G; lipase G, endothelial type; lipase, endothelial; LIPG; lipoprotein lipase H; lipose, endothelial; mEDL; PL; PRO719; UNQ387/PRO719
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 9388
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid