Tocris™ LM11A 31 dihydrochloride

Nonpeptide p75NTR ligand; neuroprotective

Manufacturer: Tocris™ 5046/50

 View more versions of this product

Catalog No. 50-465-0R

  Check Availability
Add to Cart

Disclaimers:

For Research Use Only


    Specifications

    Product Type LM11A 31 dihydrochloride
    Inhibitors LM11A 31 dihydrochloride
    Purity >98
    Molecular Weight 316.27
    Quantity 50mg

    Nonpeptide p75NTR ligand; blocks p75-mediated cell death and also increases proliferation and survival of hippocampal neural progenitors. Exhibits no effect on nerve growth factor (NGF) binding to TrkA. Prevents and reverses atrophy of cholinergic neurites, as well as reversing Alzheimer's Disease (AD) pathologies in mid- to late-stage AD mice models. Shown to promote functional recovery in a mouse model of spinal cord injury. Orally available and brain penetrant.

    • Chemical Name: (2S,3S)-2-Amino-3-methyl-N-[2-(4-morpholinyl)ethyl]pentanamide dihydrochloride
    • Formula: C12H25N3O2.2HCl
    • CAS Number: 1243259-19-9
    • Solubility: Soluble to 100mM in water and to 100mM in DMSO
    • Purity: >98

  • Description & Specifications

Related Products


Product Content Feedback

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit