LMAN1 Rabbit anti-Human, Polyclonal, Bioss

Rabbit Polyclonal Antibody

Manufacturer:  Bioss BS18304R

Catalog No. 50-198-4202

Description

The protein encoded by this gene is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi, presumably recycling between the two compartments. The protein is a mannose-specific lectin and is a member of a novel family of plant lectin homologs in the secretory pathway of animal cells. Mutations in the gene are associated with a coagulation defect. Using positional cloning, the gene was identified as the disease gene leading to combined factor V-factor VIII deficiency, a rare, autosomal recessive disorder in which both coagulation factors V and VIII are diminished.

Specifications

• Antigen: LMAN1
• Applications: Immunohistochemistry (Paraffin)
• Conjugate: Unconjugated
• Gene: LMAN1
• Format: Liquid
• Host Species: Rabbit
• Isotype: IgG
• Quantity: 100 μL
• Storage Requirements: -20°C
• Primary or Secondary: Primary
• Gene ID (Entrez): 3998

• Gene Symbol: LMAN1
• Concentration: 1 μg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene Accession No.: P49257
• Gene Alias: 2610020P13Rik; AI326273; AU043785; C730041J05; endoplasmic reticulum-golgi intermediate compartment protein 53; Ergic53; ERGIC-53; ER-Golgi intermediate compartment 53 kDa protein; F5F8D; FMFD1; Gp58; Intracellular mannose-specific lectin MR60; Lectin mannose-binding 1; lectin, mannose binding 1; lectin, mannose-binding, 1; Lman1; MCFD1; MR60; p58; Protein ERGIC-53
• Immunogen: KLH conjugated synthetic peptide derived from human LMAN1.
• Purification Method: Protein A
• Regulatory Status: RUO
• Type: Antibody
• Monoclonal or Polyclonal: Polyclonal
• Target Species: Human