LMAN1 Mouse anti-Canine, Human, Clone: OTI1E3, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA525346
DescriptionThe protein encoded by this gene is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi, presumably recycling between the two compartments. The protein is a mannose-specific lectin and is a member of a novel family of plant lectin homologs in the secretory pathway of animal cells. Mutations in the gene are associated with a coagulation defect. Using positional cloning, the gene was identified as the disease gene leading to combined factor V-factor VIII deficiency, a rare, autosomal recessive disorder in which both coagulation factors V and VIII are diminished.
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3|
|ERGIC-53, ERGIC53, F5F8D, FMFD1, MCFD1, MR60, gp58, ER-Golgi intermediate compartment 53 kDa protein, endoplasmic reticulum-golgi intermediate compartment protein 53, intracellular mannose specific lectin, intracellular mannose-specific lectin MR60, protein ERGIC-53|
|-20° C, Avoid Freeze/Thaw Cycles|
|Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot|
|Full length human recombit protein of LMAN1 produced in HEK293T cell|
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